Zollinger-Ellison syndrome

Zollinger-Ellison syndrome
a rare disorder in which there is excessive secretion of gastric juice due to high levels of circulating gastrin, which is produced by a pancreatic tumour (see gastrinoma) or an enlarged pancreas. The high levels of stomach acid cause diarrhoea and peptic ulcers, which may be multiple, in unusual sites (e.g. jejunum), or which may quickly recur after vagotomy or partial gastrectomy. Treatment with an H2-receptor antagonist or proton-pump inhibitor, by removal of the tumour (if benign), or by total gastrectomy is usually effective [M. Zollinger (1903–92) and E. H. Ellison (1918–70), US physicians]

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  • ZOLLINGER-ELLISON (SYNDROME DE) — ZOLLINGER ELLISON SYNDROME DE Le syndrome de Zollinger Ellison est une affection endocrinienne caractérisée par une hyperproduction de gastrine du fait d’une tumeur (plus souvent maligne que bénigne) ou d’une hyperplasie endocrine siégeant le… …   Encyclopédie Universelle

  • Zollinger-Ellison syndrome — Infobox Disease Name = PAGENAME Caption = Endoscopy image of multiple small ulcers in the distal duodenum in a patient with Zollinger Ellison syndrome DiseasesDB = ICD10 = ICD10|E|16|4|e|15 ICD9 = ICD9|251.5 ICDO = OMIM = MedlinePlus = 000325… …   Wikipedia

  • Zollinger-Ellison syndrome — A rare disorder caused by a tumor called a gastrinoma, most often occurring in the pancreas. The tumor secretes the hormone gastrin, which causes increased production of gastric acid leading to severe recurrent ulcers of the esophagus, stomach,… …   Medical dictionary

  • Zollinger-Ellison syndrome — noun syndrome consisting of intractable peptic ulceration with gastric hypersecretion and hyperacidity • Hypernyms: ↑syndrome * * * ¦zäliŋər¦elə̇sən noun Usage: usually capitalized Z&E Etymology: after Robert M. Zollinger died 1992 and Edwin H.… …   Useful english dictionary

  • Zollinger-Ellison syndrome — /zol ing euhr el euh seuhn/, Pathol. a condition in which a gastrin secreting tumor of the pancreas or small intestine causes excessive secretion of gastric juice, leading to intractable peptic ulcers. [after Robert Milton Zollinger (born 1903)… …   Universalium

  • Zollinger-Ellison syndrome — noun A disorder where increased levels of the hormone gastrin are produced, causing the stomach to produce excess hydrochloric acid; often caused by a tumor (gastrinoma) of the duodenum or pancreas, and resulting in peptic ulcers …   Wiktionary

  • Zollinger-Ellison syndrome — A disorder in which tumors of the pancreatic islet cells produce large amounts of gastrin (a hormone), leading to excess acid in the stomach and, possibly, a peptic ulcer (ulcer of the stomach or the upper part of the small intestine) …   English dictionary of cancer terms

  • Zollinger - Ellison syndrome — …   Useful english dictionary

  • Zollinger–Ellison syndrome — …   Useful english dictionary

  • Zollinger-Ellison-Syndrom — Klassifikation nach ICD 10 E16.4 Abnorme Gastrinsekretion Zollinger Ellison Syndrom …   Deutsch Wikipedia

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